Histology Author Michael H. Ross
ISBN-10 0781772001
Release 2011
Pages 974
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Combination text and atlas that emphasizes clinical and functional correlates of histology.

Nerves and Nerve Injuries

Nerves and Nerve Injuries Author R. Shane Tubbs
ISBN-10 9780124104471
Release 2015-04-20
Pages 700
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Nerves and Nerve Injuries is the first comprehensive work devoted to the nerves of the body. An indispensable work for anyone studying the nerves or treating patients with nerve injuries, these books will become the ‘go to’ resource in the field. The nerves are treated in a systematic manner, discussing details such as their anatomy (both macro- and microscopic), physiology, examination (physical and imaging), pathology, and clinical and surgical interventions. The authors contributing their expertise are international experts on the subject. The books cover topics from detailed nerve anatomy and embryology to cutting-edge knowledge related to treatment, disease and mathematical modeling of the nerves. Nerves and Nerve Injuries Volume 1 focuses on the history of nerves, embryology, anatomy, imaging, and diagnostics. This volume provides a greatly detailed overview of the anatomy of the peripheral and cranial nerves as well as comprehensive details of imaging modalities and diagnostic tests. Detailed anatomy of the peripheral and cranial nerves including their history and ultrastructure Comprehensive details of the imaging modalities and diagnostic tests used for viewing and investigating the nerves Authored by leaders in the field around the globe – the broadest, most expert coverage available

Compendium of Histology

Compendium of Histology Author Anders Rehfeld
ISBN-10 9783319418735
Release 2017-09-07
Pages 675
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This book has been designed to help medical students succeed with their histology classes, while using less time on studying the curriculum. The book can both be used on its own or as a supplement to the classical full-curriculum textbooks normally used by the students for their histology classes. Covering the same curriculum as the classical textbooks, from basic tissue histology to the histology of specific organs, this book is formatted and organized in a much simpler and intuitive way. Almost all text is formatted in bullets or put into structured tables. This makes it quick and easy to digest, helping the student get a good overview of the curriculum. It is easy to locate specific information in the text, such as the size of cellular structures etc. Additionally, each chapter includes simplified illustrations of various histological features. The aim of the book is to be used to quickly brush up on the curriculum, e.g. before a class or an exam. Additionally, the book includes guides to distinguish between the different histological tissues and organs that can be presented to students microscopically, e.g. during a histology spot test. This guide lists the specific characteristics of the different histological specimens and also describes how to distinguish a specimen from other similar specimens. For each histological specimen, a simplified drawing and a photomicrograph of the specimen, is presented to help the student recognize the important characteristics in the microscope. Lastly, the book contains multiple “memo boxes” in which parts of the curriculum are presented as easy-to-remember mnemonics.

Practical Gastroenterology and Hepatology

Practical Gastroenterology and Hepatology Author Keith D. Lindor
ISBN-10 9781444347876
Release 2011-07-11
Pages 424
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This comprehensive resource for fellows/trainees and candidates for recertification in gastroenterology summarizes the field in a modern, fresh format. Prominent experts from around the globe write on their areas of expertise, and each chapter follows a uniform structure. The focus is on key knowledge, with the most important clinical facts highlighted in boxes. Color illustrations reinforce the text.

The Science of Stem Cells

The Science of Stem Cells Author Jonathan M. W. Slack
ISBN-10 9781119235231
Release 2017-10-30
Pages 264
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Introduces all of the essential cell biology and developmental biology background for the study of stem cells This book gives you all the important information you need to become a stem cell scientist. It covers the characterization of cells, genetic techniques for modifying cells and organisms, tissue culture technology, transplantation immunology, properties of pluripotent and tissue specific stem cells and, in particular, the relevant aspects of mammalian developmental biology. It dispels many misconceptions about stem cells—especially that they can be miracle cells that can cure all ills. The book puts emphasis on stem cell behavior in its biological context and on how to study it. Throughout, the approach is simple, direct, and logical, and evidence is given to support conclusions. Stem cell biology has huge potential for advancing therapies for many distressing and recalcitrant diseases, and its potential will be realized most quickly when as many people as possible have a good grounding in the science of stem cells. Content focused on the basic science underpinning stem cell biology Covers techniques of studying cell properties and cell lineage in vivo and in vitro Explains the basics of embryonic development and cell differentiation, as well as the essential cell biology processes of signaling, gene expression, and cell division Includes instructor resources such as further reading and figures for downloading Offers an online supplement summarizing current clinical applications of stem cells Written by a prominent leader in the field, The Science of Stem Cells is an ideal course book for advanced undergraduates or graduate students studying stem cell biology, regenerative medicine, tissue engineering, and other topics of science and biology.

Concepts and Models for Drug Permeability Studies

Concepts and Models for Drug Permeability Studies Author Bruno Sarmento
ISBN-10 9780081001141
Release 2015-09-30
Pages 408
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This book intends to be an updated compilation of the most important buccal, gastric, intestinal, pulmonary, nasal, vaginal, ocular, skin and blood-brain barrier in vitro models for predicting the permeability of drugs. Concepts and Models for Drug Permeability Studies focuses on different approaches and comprises of various models. Each model describes the protocol of seeding and conservation, the application for specific drugs, and takes into account the maintenance of physiologic characteristics and functionality of epithelium, from the simplest immortalized cell-based monoculture to the most complex engineered-tissue models. Chapters also discuss the equivalence between in vitro cell and tissue models and in vivo conditions, highlighting how each model may provisionally resemble a different drug absorption route. Updated information regarding the most recent in vitro models to study the permeability of drugs Short and concise chapters covering all the biological barriers with interest in drug permeability A combination of bibliographic information related with individual models and footnote instructions of technical procedures for construction of cell and tissue-based models Simple and clear scientific content, adaptable for young scientists and experimented researchers

The Processes of Life

The Processes of Life Author Lawrence E. Hunter
ISBN-10 9780262299947
Release 2012-01-13
Pages 320
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Recent research in molecular biology has produced a remarkably detailed understanding of how living things operate. Becoming conversant with the intricacies of molecular biology and its extensive technical vocabulary can be a challenge, though, as introductory materials often seem more like a barrier than an invitation to the study of life. This text offers a concise and accessible introduction to molecular biology, requiring no previous background in science, aimed at students and professionals in fields ranging from engineering to journalism -- anyone who wants to get a foothold in this rapidly expanding field. It will be particularly useful for computer scientists exploring computational biology. A reader who has mastered the information in The Processes of Life is ready to move on to more complex material in almost any area of contemporary biology.

Translating Regenerative Medicine to the Clinic

Translating Regenerative Medicine to the Clinic Author Jeffrey Laurence
ISBN-10 9780128005521
Release 2015-11-18
Pages 354
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Translating Regenerative Medicine to the Clinic reviews the current methodological tools and experimental approaches used by leading translational researchers, discussing the uses of regenerative medicine for different disease treatment areas, including cardiovascular disease, muscle regeneration, and regeneration of the bone and skin. Pedagogically, the book concentrates on the latest knowledge, laboratory techniques, and experimental approaches used by translational research leaders in this field. It promotes cross-disciplinary communication between the sub-specialties of medicine, but remains unified in theme by emphasizing recent innovations, critical barriers to progress, the new tools that are being used to overcome them, and specific areas of research that require additional study to advance the field as a whole. Volumes in the series include Translating Gene Therapy to the Clinic, Translating Regenerative Medicine to the Clinic, Translating MicroRNAs to the Clinic, Translating Biomarkers to the Clinic, and Translating Epigenetics to the Clinic. Encompasses the latest innovations and tools being used to develop regenerative medicine in the lab and clinic Covers the latest knowledge, laboratory techniques, and experimental approaches used by translational research leaders in this field Contains extensive pedagogical updates aiming to improve the education of translational researchers in this field Provides a transdisciplinary approach that supports cross-fertilization between different sub-specialties of medicine

Stem Cells

Stem Cells Author Robert A. Meyers
ISBN-10 9783527668526
Release 2013-06-03
Pages 778
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This third in the Current Topics in Molecular Cell Biology and Molecular Medicine Series contains a careful selection of new and updated, high-quality articles from the well-known Meyer's Encyclopedia, describing new perspectives in stem cell research. The 26 chapters are divided into four sections: Basic Biology, Stem Cells and Disease, Stem Cell Therapy Approaches, and Laboratory Methods, with the authors chosen from among the leaders in their respective fields. This volume represents an essential guide for students and researchers seeking an overview of the field.

Carrier Mediated Dermal Delivery

Carrier Mediated Dermal Delivery Author Andreia Ascenso
ISBN-10 9781315340807
Release 2017-09-01
Pages 568
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This book presents new approaches for skin aging and photocarcinogenesis and topical formulations based on nanocarrier systems for skin disorders. It discusses cosmeceuticals, laser, photodynamic therapy, and melatonin-based treatments as important strategies for photoaging management. Photodynamic therapy and melatonin can be used in the photocarcinogenesis context, too. Therefore, the inclusion of this strong antioxidant in sunscreen products could be a promising approach. The book discusses topical formulations, including emulsions (conventional formulations and emulsions stabilized by solid particles), nail films, and nanocarriers used for the delivery of actives in various skin and nail diseases such as acne, psoriasis, atopic dermatitis, fungal diseases, leishmaniasis, and skin cancer. Finally, several nanocarriers are introduced, such as lipid vesicles (ranging from the first-generation conventional liposomes to the more recent deformable vesicles), liquid crystalline nanodispersions, gelatin, and solid lipid nanoparticles. Their composition, formulation, characterization, and topical applications are also discussed. Although this is a broad topic, the most important (nano)pharmaceutical formulations are presented in the book.

Molecular Cellular and Tissue Engineering

Molecular  Cellular  and Tissue Engineering Author Joseph D. Bronzino
ISBN-10 9781439825310
Release 2015-04-06
Pages 1891
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Known as the bible of biomedical engineering, The Biomedical Engineering Handbook, Fourth Edition, sets the standard against which all other references of this nature are measured. As such, it has served as a major resource for both skilled professionals and novices to biomedical engineering. Molecular, Cellular, and Tissue Engineering, the fourth volume of the handbook, presents material from respected scientists with diverse backgrounds in molecular biology, transport phenomena, physiological modeling, tissue engineering, stem cells, drug delivery systems, artificial organs, and personalized medicine. More than three dozen specific topics are examined, including DNA vaccines, biomimetic systems, cardiovascular dynamics, biomaterial scaffolds, cell mechanobiology, synthetic biomaterials, pluripotent stem cells, hematopoietic stem cells, mesenchymal stem cells, nanobiomaterials for tissue engineering, biomedical imaging of engineered tissues, gene therapy, noninvasive targeted protein and peptide drug delivery, cardiac valve prostheses, blood substitutes, artificial skin, molecular diagnostics in personalized medicine, and bioethics.

Antioxidants and Stem Cells for Coronary Heart Disease

Antioxidants and Stem Cells for Coronary Heart Disease Author Philip B Oliva
ISBN-10 9789814602341
Release 2014-01-22
Pages 632
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This book covers two known controversial topics — antioxidants and stem cells as therapies to treat coronary heart disease. Aiming to provide college-educated but not scientifically trained readership with a wealth of information about these two cutting-edge technologies, Antioxidants and Stem Cells for Coronary Heart Disease is written with minimum scientific terminology. Basic science studies and clinical trials regarding stem cells and antioxidants are discussed and peppered with anecdotes to make them understandable and entertaining to the laymen. Contents:Part I:The French ParadoxLDL Oxidation — BrieflyAcetylation of LDLFree RadicalsThe Oxygen ParadoxRetrolental Fibroplasia from 1956 to 1972: The Quiet TimeThe Second Epidemic of Retrolental Fibroplasia: 1972–20??Cytokines and ChemokinesLDL Oxidation by Free Radicals — In DetailTwo Other Ways to Oxidize LDL: Lipoxygenase and Nitric OxideWhat is the Raison d'être for Oxidized LDL?Fatty Streaks and Foam CellsEmbryonic Stem CellsAdult Stem CellsTransgenic MicePart II:Treatment of Coronary Heart Disease with Antioxidants: An IntroductionThe Mediterranean DietAcute Myocardial Infarctions in Japan and Norway from 1910 to 1950Wine, Beer, and Spirits as AntioxidantsA Perspective on Antioxidant Vitamins for the Treatment of Coronary Heart DiseaseVitamin AThe Thalidomide SagaVitamin CVitamin EDo Combinations of Antioxidant Vitamins Work Better than Individual Vitamins in Patients with Coronary Heart Disease?A RequiemMolecular Markers, Reporter Genes and Suicide GenesStem Cells for the Heart: Hype or Hope?The PrizefightBrainbowCre/Lox: A Cut-and-Paste Method of Gene Swapping Without a Mac or PC and a New Scientific Term with Vast SignificanceBacteriophage, Transgenic Mice and Transgenic MarmosetsPhage Geometry and Soccer BallsEuler's FormulaE = mc2 and Einstein's BrainThe Manhattan Project and Its Connection with Albert EinsteinA Gadget, a Little Boy and a Fat ManCamillo Golgi and Santiago Ramón Y Cajal: Bitter Rivals to The End Readership: College-educated general public and non-scientists who are interested in the topic of antioxidants and stem cells. Key Features:The book is written in plain English and scientific jargons are explained in laymen terms“Hot topics” such as embryonic stem cells, adult stem cells and antioxidants are discussedA well-researched and colourfully illustrated book for readers of the general publicKeywords:Stem Cells;Antioxidants;Coronary Heart Disease

Exercise and Human Reproduction

Exercise and Human Reproduction Author Diana Vaamonde
ISBN-10 9781493934027
Release 2016-03-07
Pages 351
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Providing a comprehensive review of the interactions between exercise and human reproduction, this unique text focuses on both the positive and negative consequences of sport and physical activity on male and female fertility and infertility and the biological mechanisms and processes behind them. Beginning with a review of the structure and function of the male and female reproductive systems as well as fertilization and gestation, the discussion then turns to the physiology and endocrinology of sport and exercise, which is further elaborated in subsequent chapters on the impact of physical activity, hormonal changes, pathologies, and consequences of drug use for active men and women. Additional chapters address related topics, such as the impact of sport on young athletes and developing reproductive potential, physical activity and pregnancy, the use of oral contraceptives in athletes, oxidative stress, and the impact of nutritional deficiencies on athletes’ fertility, with a final chapter providing recommendations and therapeutic guidelines for exercise-related reproductive disorders. Covering everything from the fundamental principles of sports physiology and human reproductive potential to the interaction between physical exercise and the endocrinology of the reproductive system, Exercise and Human Reproduction is an authoritative resource for helping clinicians understand how the reproductive system adapts to activity and exercise and offers strategies to avoid potential harm to human reproduction.

Advances in Molecular Toxicology

Advances in Molecular Toxicology Author
ISBN-10 9780128024300
Release 2015-11-05
Pages 300
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Advances in Molecular Toxicology features the latest advances in the subspecialties of the broad area of molecular toxicology. This series details the study of the molecular basis of toxicology by which a vast array of agents encountered in the human environment and produced by the human body manifest themselves as toxins. The book is not strictly limited to documenting these examples, but also covers the complex web of chemical and biological events that give rise to toxin-induced symptoms and disease. The new technologies that are being harnessed to analyze and understand these events will also be reviewed by leading workers in the field. Provides cutting-edge reviews by leading workers in the discipline Includes in-depth dissection of the molecular aspects of interest to a broad range of scientists, physicians and any student in the allied disciplines Presents leading-edge applications of technological innovations in chemistry, biochemistry, and molecular medicine

Well Differentiated Malignancies

Well Differentiated Malignancies Author Xichun Sun
ISBN-10 9781493916924
Release 2014-10-28
Pages 191
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Well-Differentiated Malignancies: New Perspectives is devoted to an important topic in surgical pathology which is inadequately covered by currently available books. Well-differentiated malignancies are systematically addressed with an emphasis on the tissue/cell specific malignant atypia. The key features for each malignancy are extensively illustrated with high quality pictures from authoritative sources. This book represents a daring and rarely attempted endeavor to bridge the gap between histopathology and molecular medicine in that cutting-edge molecular findings are seamlessly integrated into the key morphological features. This volume also includes discussions of short lists of organ-based benign lesions with concerning morphological features. Presented in the differential diagnosis section, they will not only serve as useful checklists for the surgical pathologist who is seriously contemplating a diagnosis of malignancy due to the observation of some cytological or histological atypia, but also help hone the key features of each malignant atypia. Well-Differentiated Malignancies: New Perspectives provides an innovative resource on the difficult topic of well differentiated malignancies for pathology residents, fellows and for those already in clinical practice.

Permeability of Biological Membranes

Permeability of Biological Membranes Author Gaspar Banfalvi
ISBN-10 9783319280981
Release 2016-02-10
Pages 263
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This book deals with biological membranes, focuses on permeabilization and pays particular attention to reversible permeabilization to maintain the viability and physiological conditions of the cells. Selective permeability of biological membranes also known as semipermeability, partial permeability or differential permeability allows molecules to diffuse, pass by passive and active or by other types of transport processes mediated by proteins. The first chapter of the book deals with the composition of biological membranes, characterizes cellular membranes of prokaryotic, eukaryotic cells, membranes of cellular organelles and the function of biological membranes. The second chapter provides an overview of bilayer permeability, selectivity of permeabilization and cellular transport processes. Chapter 3 overviews different cell manipulations that aim to make cells permeable while maintaining not only the structural but also the functional integrity of cells. The last chapter deals with applications, particularly with reversible permeabilization to study macromolecular (DNA, RNA, poly-ADP ribose) biosynthetic processes, replication, gene expression, visualization of replicons, intermediates of chromosome condensation, genotoxic chromatin changes, upon treatment with heavy metals and different types of irradiation. The interdisciplinary aspects of the book contribute to the understanding of the structure of nucleic acids, replicative intermediates, Okazaki fragments, RNA primer mechanism, subphases of replication and repair synthesis, replicons, gene expression, chromosome condensation generated a wealth of information that will attract a wide readership. The natural audience engaged in DNA research, including genetics, cell and molecular biology, chemistry, biochemistry, medicine, pharmacy will find essential material in the book.

Comprehensive Toxicology

Comprehensive Toxicology Author
ISBN-10 9780080468846
Release 2010-06-01
Pages 11200
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An explosive increase in the knowledge of the effects of chemical and physical agents on biological systems has led to an increased understanding of normal cellular functions and the consequences of their perturbations. The 14-volume Second Edition of Comprehensive Toxicology has been revised and updated to reflect new advances in toxicology research, including content by some of the leading researchers in the field. It remains the premier resource for toxicologists in academia, medicine, and corporations. Comprehensive Toxicology Second Edition provides a unique organ-systems structure that allows the user to explore the toxic effects of various substances on each human system, aiding in providing diagnoses and proving essential in situations where the toxic substance is unknown but its effects on a system are obvious. Comprehensive Toxicology Second Edition is the most complete and valuable toxicology work available to researchers today. Contents updated and revised to reflect developments in toxicology research Organized with a unique organ-system approach Features full color throughout Available electronically on sciencedirect.com, as well as in a limited-edition print version